The ilium is commonly utilised for bone harvesting, and several surgical methods have been devised to minimise the related complications. However, the discomfort experienced after surgery at the donor site might be intense, requiring the use of pain relief medication that affects the entire body, which in turn delays the ability to start moving early and hinders the patient's release from the hospital. While local anaesthetic infusion at the harvest site has been recommended as a secure and efficient approach for pain treatment, its effectiveness has not been systematically researched, and not all trials have shown enhanced pain management. AIM: To determine the best drug administration delivery method for patients undergoing secondary alveolar bone grafting. MATERIALS AND METHODS: An preliminary, randomised clinical trial was undertaken between October 2022 and October 2023. The study comprised patients who were receiving secondary alveolar bone transplantation. The parameters evaluated included pain measured using the VAS scale, early mobilisation, and the duration of hospital stay. The data entry and statistical analysis in SPSS (version 23.0) were conducted utilising the Microsoft Excel spreadsheet. The study analysed the patients after their surgery. The threshold for statistical significance was established at a p-value of less than 0.05. The paired t-test and Mann Whitney test were employed to evaluate the disparity in means of continuous variables among groups. RESULTS: The data analysis revealed that patients in group A had a substantially longer duration of pain alleviation (4.2 ± 0.62 hours) compared to group B (6.4 ± 0.43 hours) (Table 2). Group B experienced a notable delay in the time it took for them to start walking (7.2 ± 1.98 hours) as a result of inadequate pain management. Patients in Group A exhibited a notable reduction in pain score during function (4.3 ± 1.03 hours) in comparison to the other groups. However, they reported a shorter period of pain relief compared to Group B. The duration of hospitalisation and the duration of the surgical procedure were the same in both groups. CONCLUSION: Compared to local infiltration at the surgical site, the administration of bupivacaine through an IV cannula at the surgical site yielded better outcomes in terms of less postoperative pain, a shorter hospital stay, and faster mobilisation. Bupivacaine exhibits a prolonged duration of action and carries a reduced likelihood of cardiovascular and neurotoxic side effects.