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Can Combination Therapy Improve Outcomes in PDE5i-Refractory Erectile Dysfunction? A Systematic Review of Low-Intensity Extracorporeal Shockwave Therapy
Volume 8 | Issue - 8
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Influence of Storage Temperature on the Bond Performance of Universal Adhesives: A Narrative Review
Volume 8 | Issue - 8
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Effects of direct acting antivirals(DAAs)on cryoglobulinemia in patients infected with hepatitis C virus
Volume 8 | Issue - 8
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Effect of Education Sessions About Plastic Usage Hazards and Its Safe Disposal on Knowledge and Reported Practice of Female Employees at Port Said University: A Pre–Post Intervention Study
Volume 8 | Issue - 7
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Soil Quality Under a Cocoa-Based Agroforestry System With Associated Indigenous Tree Species In The Department Of Divo (Cote d’Ivoire)
Volume 8 | Issue - 7
A Cross-sectional study to evaluate aspartae platelet ratio index (APRI) as a non-invasive and cost effective predictor for the diagnosis of liver fibrosis and esophageal varices in chronic liver disease patients in a tertiary care center in south Indi
Main Article Content
Abstract
Background and Aim Fibrotic stage (FS) assessment is essential in chronic hepatitis C treatment cascade. Liver stiffness measurement (LSM) using transient elastography (TE) is reliable and correlated with liver biopsy. However, TE may not be widely available. This study aimed to evaluate the diagnostic performances of aspartate aminotransferase to platelet ratio index (APRI) and fibrosis 4 (FIB‐4) scores compared with TE. Methods We conducted a cross‐sectional study, including all chronic hepatitis C virus (HCV) monoinfection patients with successful and reliable LSM at Chettinad institue Kelambakkam. Characteristics and laboratory data within 3 months of TE were retrospectively reviewed. Using TE as a reference standard, the diagnostic performances of APRI and FIB‐4 were evaluated. TE cut‐off levels of 7.1 and 12.5 kPa represented significant fibrosis (SF) and cirrhosis, respectively
