This study was conducted for the histological analysis of gingival condition associated with orthodontic treatment with ceramic brackets. Material and methods: This study comprised of 20 subjects undergoing orthodontic treatment with ceramic brackets. The subjects were informed about the procedure and were asked to give consent. The study included the subjects who were willing to participate in the study as well as those who were undergoing orthodontic treatment. The subjects unwilling to participate in the study were excluded from the study. The subjects underwent periodontal examination to check for any gingival conditions. The findings were noted. Statistical analysis was conducted using SPSS software. Results: In this study of 20 subjects, there were 10 males and 10 females in this study. Chronic infection was seen in 10 subjects, gingival enlargement was seen in 5 subjects, mucogingival changes were evident in 4 subjects and permanent bone loss was observed in 1 subject. Papillary hyperplasia was observed in 13 subjects and tears and ulcerations in the gingival epithelium were evident in 7 cases. Conclusion: The histological analysis of gingiva of subjects undergoing orthodontic treatment revealed papillary epithelia hyperplasia and tears and ulcerations in the gingival epithelium. Clinical conditions like chronic infection, gingival enlargement, permanent bone loss and mucogingival changes were also evident in these subjects.