The use of antibiotics is essential in maxillofacial surgery. In this study, 100 patients from the oral and maxillofacial surgery department at Sree Balaji Dental College and Hospital were recruited throughout the 2018 academic year. There were two sample sizes: group A, which included 50 patients who had prophylactic antibiotic coverage following the procedure, and group B, which included 50 patients but did not receive prophylactic antibiotic coverage. Following the operation, the patient was instructed to take amoxicillin in this case of clindamycin.