The quantitative research approach, experimental study design was done, Purposive sampling technique is used to select the patients of Primary Health Care Centre (PHC) with objective to assess the effectiveness of topi cal ethyl chloride spray on pain perception who are re ceiving IM injection. Ludwing Von Bertalanffys open system theory was implemented as conceptual frame work. 10 point numerical pain scale was applied to as sess the level of pain . Post test was conducted among both experimental and non-experimental group on pa tients receiving IM injection. For experimental group Ethyl Chloride Spray was given and the post-test was conducted. The level of pain result in experimental group has decreased to 17% after using stress manage ment intervention for critical care nurses in experi mental group whereas there was only 0.94% stress has reduced in control group without intervention.