Background: The cancer cells that grow in the lip, mouth, and throat of a person is known as ‘Head and Neck’ cancer and the incidence of this particular type of cancer is very high in North East India due to frequent consumption of high amount of betel nut and tobacco by most of the inhabitant of the region. So this research work intends to perform a study on the survival pattern of Head and Neck cancer patients from North-East India. Materials and Methods: This study was based on 212 Head and Neck cancer patients treated at North East Cancer Hospital & Research Institute (NECHRI), Guwahati, from 1st January 2018 to 31st December 2018. Some standard survival analysis techniques like Kaplan–Meier product limit estimator, Log-rank test, Cox proportional hazards model, etc. Results: The present study estimated that the median survival time of Head and Neck cancer patients of Assam was 31 months (standard error = 4.115, 95% C.I. 22.93 to 39.06). The average survival time (22 months) was lower and the risk of dying was higher for the patients of the age group 60 years and above as compared to the person below 60 years. The patients who were diagnosed in stage 1 survived maximum (57 months) and those who were diagnosed in stage 4 survived minimum (12 months). Similarly, the patients from the rural area experience poor survival (24 months) and higher risk of dying as compared to the patients from urban areas.