Background: The present study was conducted for assessing the incidence of peri-implantitis in a known population. Materials & methods: One hundred patients who were set to receive dental implant therapy for prosthetic rehabilitation of missing mandibular molars were included in the study. Detailed demographic and clinical information for each patient was collected. Radiographic assessments were conducted for all participants, who were also subjected to biochemical and hematological screenings. Treatment plans were formulated based on the radiographic findings, and conventional dental implant procedures were performed on all patients. Follow-up appointments were scheduled for all participants, and records were kept for six months to monitor the occurrence of peri-implantitis.