ISSN : 2663-2187

ANTI-INFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT OF ROOT OF TECTONA GRANDIS IN ALBINO RATS

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Shubham Kumar Gupta, Manoj Kumar Mishra , Diksha Singh , Priyansu Yadav
ยป doi: 10.48047/AFJBS.6. si2.2024.5858-5868

Abstract

Following study investigates the inflammation reducing activity of the methanolic Tectona grandis roots extract in albino rats. Utilizing a well-established animal model, the research evaluates the extract's efficacy in reducing inflammation induced by carrageenan. Results demonstrate a remarkable decrease in paw edema in dosed groups compared to the control, indicating potent anti-inflammatory properties. Phytochemical analysis reveals the existing phytochemicals such as flavanoids, phenols, quinone and tannins, which are likely responsible for the observed effects. These findings suggest that Tectona grandis root extract could be a promising natural remedy for inflammatory conditions. Moreover, supplementary studies are warranted to isolate specific bioactive constituents & elucidate respective mechanisms of action.

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