Nanoparticles are smaller in size and can easily penetrate the cell line and can cause cell lysis. They possess outstanding properties like antiseptic and antimicrobial and phototoxicity on budding flora. Therefore with the recent advancement nanoparticles are broadly used in various fields either as coating medical devices, as drug delivery system. NPs are broadly divided into various categories depending on their morphology, size and chemical properties. There are various techniques for producing nanoparticles and for deposition of nanoparticles some are magnetic spluttering, physical vapour deposition, chemical vapour deposition, electrospinning etc. Among various inorganic nanoparticles zinc oxide nanoparticle is readily available, all human bodily tissues contain zinc and are cheaper to synthesis. ZnO NPs exhibit tremendous wound healing, catalytic, bio-imaging, anti-bacterial, anti-inflammatory properties making it the most suitable candidate for biomedical applications among other metal and metal oxide nanoparticles. ZnO NPs is used as a potential drug delivery vehicle for standard drugs as it provides synergistic effects for the treatment. In this study we exhibit on the anti-inflammatory and antioxidant property of ZnO nanoparticle.