ISSN : 2663-2187

ANTIDEPRESSANT ACTIVITY OF AQUEOUS EXTRACT OF EMBLICA OFFICINALIS LEAVES IN ALBINO MICE

Main Article Content

Vaibhavi Pandey, Manoj Kumar Mishra , Mandvi Tiwari , Kashish Maurya
ยป doi: 10.48047/AFJBS.6. si2.2024. 5833-5840

Abstract

In EO, the main constituent, i.e., tannic acid has non-selective monoamine oxidase activity. This study aims for assessing the EO leaves' potential as an antidepressant. The Forced swim test (F.S.T.) and the Tail suspending test (T.S.T.) in mice were the two models used in this work to evaluate the antidepressant activity in mice. After repeated oral therapy for 14 days of EO extract at rate of 100 & 200 mg/kg body weight significantly reduced the time of immobility. Additionally, leaves at this concurrent dose considerably down regulated the time of immobility in the TST following oral therapy respectively.

Article Details