Arterial hypertension is an established major and highly prevalent cardiovascular risk factor. The study aimed to use Speckle Tracking to evaluate right ventricular function in patients with systemic arterial hypertension. Acase control hospital based study which was conducted at Faculty of Medicine, Menoufia Governorate at the duration of two years started at 2020 till 2022. 150 subjects were included in this study divided into 2 groups. There was statistically significant negative correlation between interventricular septal thickness at end diastole and Tricuspid annular plane systolic excursion (TAPSE), Fractional area change (FAC %), Systolic TV annular velocity (S’) of the RV using Tissue Doppler imaging and Global right ventricular strain using two- dimensional echocardiography (%). TAPSE (mm), FAC (%), S’(cm/s) and 2D-RVGLS (%) are depressed with increasing IVSd in hypertensive group. Conclusion: RV strain parameters measured by 2D- speckle tracking echocardiography have the highest accuracy in detection of RV impairment.