The objective of this empirical, quantitative, and survey based descriptive research is to identify and compare the awareness of sanitary workers towards the impacts of heavy workload on their health. The study sampled 100 respondents from both multi-speciality and single speciality hospitals in Tirunelveli city of Tamil Nadu, India using both judgement and convenience sampling techniques. The primary data were collected using the schedule method with the help of a questionnaire, which was translated to the respondents in their mother language (Tamil). The secondary data were collected from books, journals, and projects. The percentage method has been applied to analyze the data. The results of the research show that the perception of the respondents of both kinds of organizations towards the effects - ‘tiredness; weight loss; and stress, depression, panic, and irritation’ is the same - ‘I know somewhat’; whereas, the perception of the respondents of both kinds of organizations towards the effects, sleeping problem; Diabetes mellitus; Hypertension; Cardiovascular, Respiratory, and Stomach disorders; and Stress are same – ‘I know very less’. At the same time, the perception of the respondents in both kinds of organizations is the same: ‘I know very much’ towards the factor: Getting the appearance of old age.