Ectomyelois ceratoniae, is a handicapping factor for the export of dates. The objective of this study is testing the effect of Pergularia tomentosa extract on this butterfly. Aqueous and ethanolic extracts of Pergularia tomentosa, are testing at three concentrations 5%, 10%, and 15% on eggs treated by spraying, on first-stage larvae by ingestion and on adults by inhalation. The individuals of E. ceratoniae derived from wormy dates. The highest mortality rate larvae, is obtained from the ethanolic extract. For adults, the mortality rate reaches 8.87±3,39% %; 44.44± 3.95%, 66.67±2.56% by aqueous extract and 31.11±3.39, 47.41±1.28% et 74.07 ±1.28%, for the concentrations of 5%, 10% and 15% of ethanolic extract . The lethal dose 50 in larvae is lower than that recorded by aqueous extract, under the effect of the ethanolic extract (0.051 mg/ml). In adults, LD50 are almost equal under the two types of extraction. The lowest LD 90 is noted in adults under the effect of the aqueous extract (0.532 mg/ml) followed by the ethanolic extract on the same stage (1.118 mg/ml). The LD 90 of the larvae reaches (1.98 mg/ml and 7.07 mg/ml under the effect of the ethanolic then aqueous extract respectively).