The carbazole framework serves as a pivotal structural element in numerous biologically active compounds, both synthetic and natural. Its wide array of biological activities and therapeutic applications has garnered considerable attention in research circles. Carbazole stands out as a promising base material for the synthesis of innovative drugs, given its strong pharmacophoric features and ring structure. Consequently, there's a burgeoning interest in crafting various carbazole derivatives as potential candidates for improved drug therapies across different diseases. This review offers a fresh approach for scientists to investigate this nucleus's possibility and create a new class of medications with improved therapeutic characteristics. Emphasizing the pharmacological activities of carbazole already documented by researchers, this review serves to consolidate existing knowledge and spur further advancements in diverse fields. Finally, this work provides a means by which scientists might design and create carbazole compounds with intriguing pharmacological properties.