Paeonia algeriensis Chabert is an Algerian endemic species habitually used by local people in traditional medicine. This study tried to express phytochemicals composition and biological activities of the species. CG/Ms was used to determine molecular composition, antioxidant activity was assessed by three tests (DPPH, reducing power and lipid peroxidation), antimicrobial activity was tested with four bacterial strains and one yeast, the anti- inflammatory activity was carried out by the human red blood cell (HRBC) membrane stabilization method and the In-vivo healing wounds activity by excision model. The result show a perfect antioxidant activity, a powerful antibacterial effect an important anti- inflammatory power at a low concentration and total healing wounds effect in just 13 days of experiment.