Background: Employing opioids as intraoperative analgesics constitutes a crucial element of perioperative pain management. While ensuring hemodynamic stability and mitigating somatic responses are achievable through deep anesthesia, this approach may engender slow recovery and postoperative nausea and vomiting (PONV). Hence, this study aimed to analyze the efficacy of intravenous opioid anesthetic drugs across both intraoperative and postanesthetic recovery stages to optimize postoperative conditions.