Background: Orthodontic tooth movement is a time-consuming process that can be a concern for both patients and practitioners. Micro Osteoperforation is an emerging technique that may accelerate tooth movement by inducing localized alveolar microtrauma. This study aimed to compare the effectiveness of Micro Osteoperforation using Temporary Anchorage Devices and Bone Drilling Bur on the rate of canine retraction in the maxillary arch. Method: A clinical trial was conducted involving 28 patients with bimaxillary protrusion requiring upper first premolar extraction. Two groups were formed, one with receiving Micro Osteoperforation with Temporary Anchorage Devices and the other with Bone Drilling Bur. Canine retraction rates were measured monthly for eight months using digital vernier calipers. Outcome of the study: The study demonstrated that MOP significantly increased the rate of canine retraction in the experimental groups compared to the control groups. However, there were no statistically significant differences between the Temporary Anchorage Device and Bone Drilling Bur methods. Conclusion: Microsteoperforation, whether performed with Temporary Anchorage Devices or Bone Drilling Bur, proved to be an effective method for accelerating canine retraction in the maxillary arch. This has clinical implications for reducing orthodontic treatment duration and improving patient comfort. Further research is recommended using more extensive sample sizes and extended follow-up periods to confirm and build upon these findings.