ISSN : 2663-2187

“Comparison of Motor and Hemodynamic Profile of Epidural Levobupivacaine 0.5% And 0.5% Racemic Mixture Bupivacaine in Patients Coming For Elective below Umbilical Surgery”

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Dr. Ashok Kumar Balasubramanian
» doi: 10.33472/AFJBS.6.14.2024.4261-4273

Abstract

This study was performed to compare the motor and hemodynamic profile of 0.5% racemic Bupivacaine and 0.5% Levobupivacaine, in patients undergoing below umblical surgery.surgery. Methodology 56 patients, ASA grade 1 and 2, were randomised to receive an epidural injection of study drug (17 ml 0.5% racemic Bupivacaine in group R and 17 ml of 0.5% Levobupivacaine in group L. (Group R VS Group L) Even though, the onset of motor block was comparable in both the groups, Group L showed earlier onset of motor block at 5 min after zero time. (P value 0.002).The regression of motor block was faster in group L (p value 0.042).The time to obtain maximum level of motor blockade was found to be faster in Levobupivacaine group.(p value of 0.043).The number of patient obtaining MBS score of 3 was 62.5% in racemic Bupivacaine group and 37.5% in levobupivacaine group. The grade of motor block showed that, the levobupivacaine group had lesser grade than that of racemic group (p value of 0.016). The duration of motor block was similar in both the groups. The haemodynamic profile MAP, SpO2 and HR were similar. Conclusion:Both 0.5% levobupivacaine and 0.5% bupivacaine produced effective epidural anaesthesia and their effects were clinically indistinguishable. Levobupivacaine produces less denser and shorter duration of motor block hence they can be used for labor analagesia, postop epidural analgesia and for ambulatory surgery.

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