Oroxylum indicum, commonly called the Indian trumpet tree, is a tropical species that grows in India, Malaysia, Indonesia, China, Sri Lanka, and Japan. Numerous chemical compounds, including biochanin-A, tetuin, anthraquinone, ellagic acid, baicalein—including its 6- and 7-glucuronides—scutellarein and aloe-emodin—can be extracted from the various portions of this plant. Components of plant are extremely useful for the traditional medicine and Ayurveda to recover from range of diseases, including diarrhoea, cancer, ulcers, fever, and jaundice. According to current research, this plant has anticancer, antioxidant, antibacterial, antimutagenic, hepatoprotective, photocytotoxic, antiproliferative, antiarthritic, and anti-inflammatory properties. It also functions as an immune stimulant. The Oroxylum indicum may face threats such as habitat loss due to deforestation, land conversion for agriculture, and urbanization. Therefore, it required serious efforts to conserve this important plant species. Oroxylum indicum is a significant plant species with various ecological, cultural, and medicinal importance. Therefore, this review majorly explains medicinal properties and conservation strategies of Oroxylum indicum.