ISSN : 2663-2187

Correlation between Vitamin D levels and HbA1c in patients with Type 2 Diabetes mellitus: Systematic review with Meta-Analysis

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Vijaya Sorganvi, Muragesh Math, Rekha Udgiri, Manjula, Rachel Sushmita Daniel
» doi: 10.48047/AFJBS.6.14.2024.1354-1378

Abstract

This review synthesizes findings from 21 studies conducted over 11 years to investigate the correlation between vitamin D levels and HbA1c in individuals with type 2 diabetes mellitus in India. Searches were conducted across multiple databases and included studies from 2012 to 2022. A total of 926 participants (387 females, 539 males) were included in the analysis. The majority of studies (18 out of 21) reported a mild negative correlation between vitamin D levels and HbA1c, while three studies indicated a mild positive correlation. A meta-analysis revealed a statistically significant overall pooled relationship (pooled r = -0.16, p = 0.005, 95% CI: -0.28 to -0.05), indicating that higher vitamin D levels are associated with lower HbA1c levels.

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