ISSN : 2663-2187

DESCRIPTION OF THE INFLUENCE OF 1-O-GALLOYL-4,6- HEXAHYDROXYDIPHENOYL-β-D-GLUCOSE AND 1,2,6-TRI-OGALLOY-β-D-GLUCOSE HYDROLYZABLE TANNINS ON THE TRANSPORT OF Ca2+ -IONS IN THE SARCOPLASMATIC RETICULUM

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Mutalipov Azizbek Abdullajon o'gli, Zaynabiddinov Anvar Erkinjonovich, Kholmirzayeva Madina Akromjonovna, Usmanov Pulat Bekmuratovich, Juraboev Shakhriyor Gayratbekovich ., Rakhimov Rakhmatillo Nurallievich
» doi: 10.33472/AFJBS.6.8.2024.72-78

Abstract

In this work, 1-O-galloyl-4,6-hexahydroxydiphenoyl-β-D-glucose (1-GT) and 1,2,6-tri-O-galloyl- β-D-glucose (2-GT) hydrolyzable tannins in rat the role of sarcoplasmic reticulum (CR) Ca2+ -carrying systems in the vasorelaxant effect on aortic smooth muscle was studied. The contraction activity of aortic muscle preparations was measured in vitro using a Grass FT-03 mechanotron (Grass Instrument, USA) and a signal amplifier device that record the force of muscle contraction using the mechanographic method

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