ISSN : 2663-2187

Design, Development and Characterization of Moringa oleifera Gel

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Shailja1, Pawan Jalwal1, Amit1, Radha Rani, Anshika Saini, Arun Kumar, Priyanka Kundu, Deepak
» doi: 10.33472/AFJBS.6.Si2.2024.2694-2714

Abstract

Moringa oleifera (Family: Moringaceae) commonly called as Drumstick tree, Horseradish tree or Ben tree is an important medicinal herb referred as a miracle tree as all the parts of the plant possess nutritional and medicinal properties. The leaves of Moringa oleifera were air-dried for 12 days and then ground to a fine powder with a mortar and pestle.The ethanol extract gave a higher yield than the aqueous extract of M.oleifera leaves with 66.48% and39.5% respectively. The level of flavonoids, tannins, total phenols, saponin and alkaloids in aqueous extract of Moringa oleifera leaf meal were 3.63, 1.26, 2.04, 0.61 and 1.13% respectively. In vitro diffusion study of M.oleifera leaf extract hair gel of formulations F1 – F6 was found to be in 75.21 to 90.73% for 8 hrs. Of them the formulation F5 indicates the fastest diffusion with 90.73%.Out of all the models, Higuchi model showed the highest R2 value for in-vitro release data for F5 (0.987) followed by Korsemeyer-Peppas model (0.985). The stability studies were directed for the optimized formulation, F5 for 3 months. No considerable changes were settled for the proven limits like appearance, pH, extrudability, spreadability, gel strength, viscosity, and antifungal action at both temperatures (room temperature and 40ºC) for 3 months.

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