In different countries of the world, special importance is attached to the physiological control of athletes during the competition and during training, as well as to the assessment of the hormonal changes occurring in their bodies. Hormonal changes lead to a decrease in athlete endurance, mental stress, and work capacity, which reduces the chances of athletes to succeed in the world Olympics. In this regard, controlling physiological hormonal changes in Uzbek athletes is one of the most important current problems in order to achieve high goals.