Background/aim: One of the key factors in successful treatment outcome for prosthodontics treatment is establishing the correct orientation of occlusal plane. So much research has been done in determining the correct plane of occlusion, still confusions exist regarding universal acceptable approach in determining the plane of occlusion. Study was aimed to find out the relation between inclination of occlusal plane and facial outline, age and gender in completely dentate patients Materials and methods: Lateral cephalographs were selected from the department of Oral medicine and Radiology, based on inclusion and exclusion criteria. All the selected radiographs were traced for occlusal plane and Frankfurt Horizontal plane. Angle between these two planes were studied based on facial profile, age and gender of the cephalographs. Correlation was established using independent regression analysis. Results: There was significant correlation between gender and occlusal plane angle. In males it was found to be more as compared to than that of females. There was no significant correlation found with occlusal plane as related to age and facial profile of the selected samples. Conclusion: While fabricating the complete dentures, occlusal plane can be adjusted more steeper in males as compare to than that of females. Further studies with larger samples are needed to establish correlation with age and facial profile.