Purpose: The study was conducted to evaluate the crestal bone loss, and the buccal plate thickness (BPT) around dental implants as influenced by diode laser versus PRF using (CBCT) Cone Beam Computed Tomography, in implant supported over denture. Material and method: 24 completely edentulous patient except for the lower first premolars were selected and received lower implant supported over denture. The patients were randomly and equally divided into two groups, where group (A) subjected to PRF before implant insertion and group (B) subjected to low level laser treatment LLLT immediately after implant insertion, then after 3rd, 7th, 15th days from implantation. Using CBCT, both the crestal bone loss and buccal plate thickness were measured at the time of implantation, and 9 months after implant insertion. Results: The crestal bone loss differences between the two-time intervals were tested at (P- value ≤ 0.001). The two groups (A&B) were equal at baseline (10±0.00 mm), and both groups showed significant bone loss at 9 months, where group (A) was (8.74±0.12 mm) and (8.05±0.53) for group (B). Comparing the two groups at 9 months, revealed statistically significant increase for group (B) in crestal bone loss as it achieved the highest percentage of bone loss. Conclusion: According to the present study, it could be concluded that, both techniques LLLT and PRF are successful and the PRF showed better results comparing with LLLT regarding crestal bone loss and buccal plate thickness around dental implants