Background: Evidence suggests that considerable number of children receive suboptimal care for injection-related pain, which may have long-term deleterious impacts on development and future pain tolerance. Hence this study was directed to study the effectiveness of Buzzy in pain reduction following intramuscular injection. Methodology: An open randomised trial was conducted in the pediatric OPD of a tertiary care hospital in Chengalpattu. 70 participants were enrolled based on inclusion and exclusion criteria into the study group and control group respectively. Following injection, the pain perceived was observed using the FLACC scale. Results: The mean age of buzzy bee group was 10.15  6.5 months whereas it is 9.85  6.1 in control group. Female participants were predominant in both the groups.When compared to control group, buzzy bee group had reduced mean pain score at 0 and 5thminute following vaccination. Also, buzzy bee was found effective in pain reduction at 0-minute (p < 0.001). Conclusion: Buzzy bee was found to be effective in pain reduction and can be used by paediatrics healthcare team as it is cost-effective and relatively easy to use.