Background : After menopause women will experience hypoestrogens due to loss of ovarian activity, causing changes in vaginal tissue, endometrial tissue and bone. The purpose of this study was to determine whether the effect of red bean extract with phytoestrogen content in it can be an alternative estrogen replacement therapy on estradiol levels, vaginal mucosal epithelial thickness, endometrial thickness and femoral bone osteoclasts in menopausal rats