Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
This research investigated the phytochemical composition and biological activities of a novel plant extract, extract of the leaves of Emblica officinalis Gaertn. (EOME-L). Preliminary phytochemical analysis revealed the presence of alkaloids, terpenoids, glycosides, phytosterols, flavonoids, phenols, saponins, and tannins, suggesting potential therapeutic benefits such as anti-inflammatory, antioxidant, antimicrobial, laxative, and cholesterol-lowering effects. The Borntrager test confirmed the presence of anthraquinones, further enhancing the extract's antimicrobial properties. Spectrophotometric analysis quantified the total phenolic content of EOME-L, providing valuable insights into its antioxidant capacity. In vitro assays demonstrated significant antioxidant activity, metal chelating ability, and lipid peroxidation inhibition, highlighting EOME-L's potential in combating oxidative stress-related conditions. Additionally, EOME-L exhibited potent hepatoprotective effects in CCl4-intoxicated HepG2 cells, comparable to the standard hepatoprotective agent Silymarin. Furthermore, combination therapy with EOME-L and Silymarin demonstrated synergistic hepatoprotective effects, offering a promising strategy for improving liver health. In conclusion, this research elucidated the phytochemical profile and therapeutic potential of EOME-L, emphasizing its utility as a natural remedy for oxidative stress and liver-related disorders.