ISSN : 2663-2187

Evaluation of correlation between DNA methylation and tobacco use in oral potentially malignant disorders

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Dr. Mimansha Patel, 2. Dr. Pankaj Gupta, 3. Dr. Koyel Jana, 4. Dr. Ketki K Thakare, Dr. Shilpa Wasu, Dr. Kriti Sao
ยป doi: 10.33472/AFJBS.6.8.2024.293-312

Abstract

Background:. DNA methylation is a potential approach for "cancer therapeutics" and can help researchers truly understand the genomic mechanism that leads to cancer. Tobacco consumption is considered as most important risk factor for development of oral potentially malignant disorders (OPMDs). Tobacco either in the smokeless form, smoked form may contribute to development of OPMDs. It is not clear whether DNA methylation is associated with tobacco use in patients with OPMDs.

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