ISSN : 2663-2187

Evaluation of the Role Of H-Ras in Tumorigenesis of Salivary Glands Tumors at Immunohistochemical and Molecular Biological Levels

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Pasant Tarek Thakeb, Azza Elsisi, Sherif Elnagdy, Hoda Ismail, Doaa Abdallah Farag
ยป doi: 10.33472/AFJBS.6.8.2024.1418-1426

Abstract

This study evaluates immunohistochemical (IHC) expression of H-Ras proteins in cases of pleomorphic adenoma (PA) and Warthin tumors (WT) as benign salivary tumors and mucoepidermoid carcinoma (MEC) and adenoid cystic carcinoma (AdCC) as malignant salivary tumors. The study was conducted on 37 formalin-fixed, paraffin-embedded (FFPE) tissue blocks of salivary gland tumors (17 MEC cases, 14 AdCC cases, 4 cases of PA, 2 cases of WT).

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