Dyslipidaemia is a key risk factor for cardiovascular disease (CVD), a leading cause of death worldwide. Traditional CVD risk factors like smoking, high blood pressure, cholesterol, diabetes, and obesity increase atherosclerosis risk. This pilot trial examines homoeopathic therapy as a key CVD preventive strategy for middle-aged dyslipidaemia men. The study examined how individualised homoeopathic treatments and lifestyle changes reduced cholesterol levels, improved cardiovascular health, and prevented CVD. The study included 15 men aged 36–55 who underwent socio-demographic screening, medical history, and lifestyle assessments. Lipid profiles, FBS, and HBA1c were tested. All individuals got customised homoeopathic treatments and lifestyle changes and were assessed after three months for the Framingham Risk Score (FRS). Results demonstrated considerable blood pressure, sugar, and cholesterol reductions. Total cholesterol, LDL cholesterol, and triglycerides fell while HDL rose. Weight and BMI decreased significantly, lowering cardiovascular risk scores. In dyslipidemic patients, homoeopathic treatment may improve lipid profiles and CVD risk factors. These results need to be confirmed with larger samples and longer follow-up