Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
This present study aimed to perform the fabrication and characterization of microsphere formulations of oxcarbazepine, converging on drug loading capacity, encapsulation efficiency, particle morphology, yield percentage, swelling index, mucoadhesive properties, and in vitro drug release kinetics. The formulations demonstrated consistent drug loading capacities and high encapsulation efficiencies, indicating robust and reproducible processes. Particle size analysis and SEM provided insights into particle uniformity and surface characteristics. The yield and swelling indices varied, identifying formulations OXCF-2 and OXCF-6 as optimal due to their high production efficiency and controlled release properties. The mucoadhesive analysis revealed that OXCF-6 and OXCF-2 maintained superior adhesion, beneficial for extended drug delivery applications. Kinetic modelling suggested that the drug release from these formulations predominantly follows zero-order kinetics, suitable for maintaining steady therapeutic levels. The study demonstrated the importance of a multi-faceted approach in developing effective microsphere drug delivery systems.