Background: In this study, the ionic gelation technique was used to prepare chitosan nanoparticles. During the preparation step, the NPs were loaded with Rizatriptan Benzoate. Materials and Methods: These NPs were characterized in terms of size, charge, morphology, drug loading, and drug release. Particle Size and Zeta potential were found to be 476.6 nm 22.6mv respectively. In-vitro Drug release was found to be 84.20% after 24 hr for optimized formulation. Separately, buccal films were prepared, and their properties were optimized in terms of weight, surface pH, thickness, folding endurance, and mucoadhesion. After that, the NPs were dispersed in the films and characterized for in-vitro drug release kinetics. Results: The thickness of buccal films was found between 0.179 ± 0.012 to 0.275 ±0.015 mm, and buccal films exhibited good folding endurance. In vitro disintegration and dissolution times were measured twice and were found to be around 7.80 ± 0.25 to 12.94 ± 0.15 min and 32.87 ± 1.26 to 64.68 ± 0.61 min, respectively. Surface pH was found to be between 6.75 ± 0.07 to 6.78 ± 0.09. Conclusion: The release of Rizatriptan Benzoate from the RCNPs buccal films followed a first-order kinetics and a non-fickian Super Case II diffusion. The results suggest that RCNP buccal films could be a potential candidate to achieve optimum drug release for effective treatment of migraine.