ISSN : 2663-2187

FORMULATION AND DEVELOPMENT OF SUSTAINED RELEASE TABLET OF BCS CLASS III DRUG BY USING NATURAL POLYMER

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Sandip B. Ahire, Momin Abuzer*, Pratik D. Patil, Vinod A. Bairagi, A.B. Gangurde, Osama Tauseef, Rahil khan, Ansari Mohammed Shoaib
ยป doi: 10.48047/AFJBS.6.13.2024.6613-6621

Abstract

The development of sustained release tablets for BCS Class III drugs, which are characterized by high solubility and low permeability, presents a unique challenge in pharmaceutical formulation. This study aims to formulate and develop a sustained release tablet utilizing natural polymers, focusing on enhancing the drug's bioavailability and therapeutic efficacy. Natural polymers offer several advantages, including biocompatibility, biodegradability, and minimal side effects, making them ideal candidates for sustained release formulations. The research involves the selection and characterization of Bhara Gum and Gum Karaya, formulation development, and comprehensive evaluation of the tablet's physical and chemical properties. Key parameters such as drug release profile, dissolution rate, and stability are assessed to ensure consistent and prolonged drug release. The goal is to achieve a formulation that provides sustained therapeutic action, reduces dosing frequency, and enhances patient compliance. This study contributes to the growing field of natural polymer applications in drug delivery systems, offering potential for improved treatment outcomes for BCS Class III drugs

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