The utilization of fenugreek gum, a naturally occurring super disintegrant, in developing a fast-acting cimetidine drug delivery system, was investigated. A thorough physicochemical investigation was performed on the extracted gum. An Electro Lab Dissolution Tester USP II (USP Dissolution Apparatus Type II) running at 50 rpm, 37 ± 0.5°C,and 900 ml of medium volume was used for an in vitro drug release investigation. F3 performed better than the other tested formulations, reaching a maximum drug release of 98% in 25 minutes. This finding emphasizes fenugreek gum's potential as a useful ingredient for quickly dissolving prescription pills. The findings add to continuing efforts to use natural and biocompatible materials in improving drug delivery systems by supporting more research andpossible clinical applications.