Background: Oral medication administration is perhaps the most common method of the dosage form. Researchers have been encouraged by recent technological advancements to produce Fast disintegrating tablets (FDTs) to enhance patient compliance and accessibility. The study was designed to evaluate the composition and efficacy of herbal fast disintegrating tablets for headache care. Herbal powder extracts of Salix alba L (White Willow bark), Tinospora cordifolia (Guduchi), Achyranthes aspera (Latjira), Cyprus rotundus (Nagarmotha), and Withania somnifera (Ashwagandha) are produced and processed into fast disintegrating tablets using a super disintegrant including cross povidone, sodium starch glycolate, and micro-crystalline cellulose in various ratios.