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Strategies for Teaching Vocabulary Effectively to ESL Students: Identifying and Resolving Challenges : An Emperical Study
Volume 7 | Issue - 1 articles in press
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Perceiving the Self and Others: A Phenomenological Analysis of Character Consciousness in Anita Nair's Fiction
Volume 7 | Issue - 1 articles in press
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Soft Skills: The Catalyst for Critical Thinking in Engineering Education
Volume 7 | Issue - 1 articles in press
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A Comprehensive Framework for Exploring and Evaluating Learning Digital Resources in English Language Classrooms
Volume 7 | Issue - 1 articles in press
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EXPLORATION OF INDIGOFERA PROSTRATE AGAINST OXIDATIVE STRESS AND EVALUATION FOR NEUROPROTECTION IN CHEMICALLY INDUCED NEUROTOXIC RATS
Volume 7 | Issue - 1 articles in press
Formulation, Characterization and Optimization of Fast Dissolving Tablet of Celecoxib
Main Article Content
Abstract
This study aimed to enhance the solubility and dissolution rate of celecoxib, a COX-2 inhibitor known for its anti-inflammatory and analgesic properties, by formulating fast dissolving tablets (FDTs) using solid dispersion with polyvinyl pyrrolidone K30 (PVP-K30). Various ratios of celecoxib to PVP-K30 were investigated, with the 1:4 ratio yielding the highest solubility compared to the pure drug. The dissolution rate of the FDTs were assessed in 2% SLS solution, with the in-vitro release ranked based on the percentage of drug released after 50 minutes
