ISSN : 2663-2187

FORMULATION & EVALUATION OF GEL CONTAINING CAMELLIA SINENSIS OIL FOR TREATMENT OF BURN SKIN

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Rishika Sharma, Gaurav Ahirwar ,Shubham Ambawatiya. Sonam Chaturvedi
ยป doi: 10.48047/AFJBS.6.13.2024.6545-6552

Abstract

Burns is a tissue damage caused by contact with hot objects, chemical electrical and radiation. Damage caused by burns can come to the subcutaneous tissue, dermis and epidermis depends on the length of exposure to the causative factor. Burns are usually expressed by degrees, depending on the extent of tissue damaged by burns proficiency level. In recent time the Gel based drug delivery systems are being employed for therapeutic effectiveness of topical applied drugs. Camellia sinensis is traditionally showed anti microbial , anti-inflammatory agent, analgesic & antioxidative properties. Topical route for Camellia sinensis oil extract gel was selected up to avoid GIT irritation and to maximize the drug concentration at the site of action. The Camellia sinensis extracted oil gel are prepared by using different conc. of Carbopol 940 .From the result it is concluded that all the gel formulation showed good apperanence and homogeneity. The physical appearance of the gel formulation yellowish brown in nature. The pH of gel formulation wasin the range of 6.8, which lies in the normality pH of skin and wit time no skin irritation was observed by small amount odd shear diameter after 1 min of herbal gel was between 37 mm which indicate good spread ability of herbal gel. The result showed that Camellia sinensis oil extract for formulation of burning gel was better than the effect of the other gel.

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