Bacteriophages isolated from river Ganga water are known as Ganga river bacteriophages. It has recently been discovered that Ganga river bacteriophages, which are naturally occurring predators of bacteria, can be effectively employed in contemporary biotechnology. For numerous bacterial strains that are resistant to antibiotics, they have been suggested as antibiotic substitutes. Phages from the Ganga river can be employed as biocontrol agents in the oil and agricultural sectors. Additionally, ganga river phages are employed as delivery systems for several proteins and antibodies, as well as for DNA and protein vaccines for the identification of harmful bacterial strains. Ganga River bacteriophages are a varied set of easily manipulable viruses that may have applications in research, biotechnology, and medicine. This review article's objective is to help the many academics, researchers, and biotechnologists who are utilising Ganga river phages in their practice, to accelerate the progress and development in the field of biotechnology