Green nanotechnology, characterized by the integration of sustainable principles into nanomaterial design and application, holds promise for revolutionizing cancer treatment strategies. This abstract provides an overview of the potential of green nanotechnology in the context of photodynamic therapy (PDT) for cancer treatment. We discuss the principles of green nanotechnology, recent innovations in sustainable drug delivery, and the advantages it offers over traditional approaches. Additionally, we explore the mechanism of action of PDT, its challenges in cancer treatment, and the importance of PDT in sustainable oncological interventions. Emerging trends and research directions in green nanotechnology, including nanotheranostics, stimuli-responsive nanomaterials, and nanoparticle-mediated immunomodulation, are highlighted. Furthermore, we address the challenges and considerations in the development and application of green nanotechnology for PDT, emphasizing the need for multidisciplinary collaboration and innovative solutions to overcome barriers to clinical translation. Overall, green nanotechnology presents a promising avenue for sustainable and personalized cancer treatment, offering novel therapeutic approaches that prioritize patient well-being and environmental stewardship.