ISSN : 2663-2187

Grewia asiatica (Phalsa) fruit juice catalysed synthesis of some biologically active dihydroprimidinone derivatives under microwave irradiation.

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Anupma Singh & Bandana Dwivedi
» doi: 10.48047/AFJBS.6.14.2024.10391-10403

Abstract

The dihydropyrimidinone derivatives were synthesized by Biginelli reaction employing equimolar amount of acetoacetic ester, urea and substituted aromatic aldehyde using grewia asiatica fruit juice as biocatalyst under microwave irradiation. The synthesized dihydropyrimidinones were evaluated for their antibacterial activity against S. aureus and E.coli, by cup-plate agar diffusion method.

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