The authors conducted a study among women of fertile age in menopause, where they identified a pathological state of health against the background of a lack of the hormone TSH and free T4. A condition survey was conducted consisting of 15 questions, examination of the skin, muscle tone, swelling in the extremities, BMI, palpation and ultrasound of the thyroid gland. Characteristic pathological conditions for this age were identified, and therefore the authors suggest early prevention of this disease in order to improve the quality of life of patients.