Aim: This review assesses the recent Randomized Controlled Trials (RCTs) in Cardio-pulmonary Rehabilitation. It focuses on innovative therapies to enhance the outcomes of patients and identify new research domains in cardiopulmonary rehabilitation. Method: The review looks at studies on sleeping positions that are somewhat upright for obstructive sleep apnea. Text messaging can be used in cardiac and lung rehabilitation programs. Hospitals can offer online singing sessions as a part of the structured lung rehabilitation program. The effectiveness of cardiopulmonary rehabilitation can be measured through patient compliance, quality of life, physical activity, breathing exercises, and overall health conditions.