Polycystic ovary syndrome (PCOS) presents a significant challenge in managing infertility due to its complex pathophysiology. Recent advancements in reproductive technologies offer promising avenues to improve fertility outcomes in women with PCOS. This review explores the latest advancements and their impact on fertility outcomes in this population. In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) have emerged as key treatments for PCOS-related infertility. These techniques enable precise control over ovulation induction and gamete manipulation, addressing the irregularities in ovarian function characteristic of PCOS. Moreover, the use of gonadotropin-releasing hormone (GnRH) agonists for oocyte triggering has shown efficacy in reducing the risk of ovarian hyperstimulation syndrome (OHSS) in PCOS patients undergoing IVF. Additionally, lifestyle interventions focused on weight management have gained prominence as a cornerstone of PCOS management, with studies demonstrating the beneficial effects of weight loss on restoring menstrual regularity and spontaneous ovulation. Pharmacological agents such as metformin, liraglutide, and aromatase inhibitors offer alternative options for ovulation induction in cases resistant to conventional treatments like clomiphene citrate. Overall, the integration of these advancements in assisted reproductive technologies (ART) and individualized treatment approaches holds promise for optimizing fertility outcomes in women with PCOS. However, further research is warranted to refine treatment protocols, enhance success rates, and minimize potential risks associated with these interventions.