Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
In the present study includes environment benign synthesis, characterization, and evaluation of biological activities of new ligand N-((4-amino-5-mercapto-4H-1,2,4-triazol-3-yl)methyl)isonicotinamide (NAMTI) and it’s metal complexes with copper(II), nickel(II) and cadmium(II). The ligand and its complexes were synthesized using a microwave synthesizer and characterized through various analytical techniques including UV-Vis, FT-IR, NMR spectroscopy, elemental analysis, TGA, and cyclic voltammetry as well as conductivity and magnetic moment data. The synthesized compounds were evaluated for their antibacterial and antifungal activities against selected microbial strains. The antibacterial activity was assessed using the Kirby-Bauer technique, and the results indicated significant activity of Cu(NAMTI)₂ and Cd(NAMTI)₂ complexes, often comparable to the standard antibiotic Gentamycin. The antifungal activities were evaluated using Mueller Hinton agar plates, with notable inhibition zones observed for the synthesized complexes. The study highlights the potential of Cu(NAMTI)₂ as a promising antibacterial agent and provides insights into the redox behavior of the metal complexes.