ISSN : 2663-2187

Novel Acridine Derivative Inhibiting Acetylcholinesterase: In Silico Molecular Docking Studies For Alzheimer's Disease Treatment

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Poornima M , Magesh M , Vasanthy L1 , Lakshmi priya SK1 , Sheela M2 , Dhanapriya S ,Harish V H ,Mahalakshmi D
» doi: 10.33472/AFJBS.6.10.2024.180-197

Abstract

Alzheimer's disease (AD) is a neurodegenerative brain disorder that causes diminished memory and cognitive decline, and it affects millions of people throughout the world. In particular, acetylcholinesterase (AChE) inhibitors have been studied as a means of studying the cholinergic system, since low acetylcholine levels, T protein aggregation, oxidative stress, inflammatory processes, and abnormal beta-amyloid, are all related to AD

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