Background Marginal leakage in provisional crowns can lead to complications such as secondary caries, pulpal irritation, and periodontal disease. The choice of temporary luting cement plays a crucial role in minimizing these issues. This study aims to comparatively evaluate the marginal leakage of provisional crowns cemented with different temporary luting cements. Materials and Methods An in vitro study was conducted using 60 extracted human premolars. The teeth were divided into three groups (n=20) based on the type of temporary luting cement used: Group A (Zinc Oxide Eugenol), Group B (Non-Eugenol Zinc Oxide), and Group C (Resin-based cement). Provisional crowns were fabricated and cemented using the respective cements. The specimens were thermocycled for 500 cycles between 5°C and 55°C, then immersed in a 2% methylene blue dye solution for 24 hours. The teeth were sectioned longitudinally, and the extent of dye penetration was measured using a stereomicroscope. Results The mean dye penetration values were as follows: Group A (1.5 ± 0.3 mm), Group B (1.0 ± 0.2 mm), and Group C (0.5 ± 0.1 mm). Statistical analysis using ANOVA and post-hoc tests revealed significant differences between the groups (p<0.05). Resin-based cement (Group C) showed the least marginal leakage, followed by Non-Eugenol Zinc Oxide (Group B) and Zinc Oxide Eugenol (Group A).