Periodontitis is a disease characterized by inflammation, infection, and destruction of the periodontium, and it can greatly affect human oral as well as general health. This study addresses this issue by examining the association between periodontal disease in children and cardiovascular diseases (CVDs). In fact, gingivitis is a common form of gingival tissue disease that can turn into periodontitis, which subsequently affects the supporting structures of human teeth, including the gingiva itself, alveolar bone, and periodontal ligament. The research conducted in this field until today shows that periodontal diseases can cause the risk of cardiovascular diseases by causing systemic inflammation and releasing inflammatory markers including C-reactive protein and interleukin-6. To increase Children who suffer with periodontal disease have even higher levels of these markers, suggesting a potential link involving cardiovascular complications.