Background: Cognitive dysfunction, a major health problem in 21st century is one of the most functionally demoralizing characteristic of many neuropsychiatric and neurodegenerative disorders which can be overcome by use of Rasayana plants which are believed to have Neuroprotective property. In the present study, Adhatoda vasica (Leaves) and Vigna Mungo (Seeds) were selected to assess its memory enhancing potential. Material and methods: The plant parts were collected; authenticated; shed dried and successively extracted using different solvent according to polarity. The extracts were subjected to various chemical analyses like Estimation of phytoconstituents, Inhibition of lipid peroxidation, antioxidant activity against free radicals and inhibition of Acetylcholine esterase enzymes. The acute and chronic toxicity studies were performed within prescribed guideline set by OECD. The Evaluation of Memory Enhancing Activity was carried out by Morris Water test and Elevated plus Maze test. The Biochemical Estimation was carried out by Acetyl cholinesterase inhibition activity. The extracts and their fractions were subjected to characterization by different spectroscopic and chromatographic techniques. Finally isolated fractions subjected to pharmacological studies