The management of inflammatory processes in periapical tissues during pregnancy presents unique challenges due to potential adverse effects on maternal and fetal health. This article explores strategies for the prevention of complications arising from such inflammatory conditions in pregnant women. By reviewing current literature and clinical practices, this study elucidates various preventive measures, including timely dental interventions, antimicrobial therapies, and prenatal care coordination. Additionally, it examines the importance of interdisciplinary collaboration between obstetricians and dentists to ensure optimal outcomes for both mother and child. The article concludes with recommendations for healthcare providers to mitigate the risks associated with periapical inflammation in pregnant individuals, promoting maternal well-being and fetal development.